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Alu-polymerase chain reaction genomic fingerprinting technique identifies multiple genetic loci associated with pancreatic tumourigenesis

โœ Scribed by Arthur B. McKie; Takeshi Iwanamura; Hing Y. Leung; Michael A. Hollingsworth; Nicholas R. Lemoine


Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
12 KB
Volume
19
Category
Article
ISSN
1045-2257

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Alu-polymerase chain reaction genomic fi
โœ Arthur B. McKie; Takeshi Iwamura; Hing Y. Leung; Michael A. Hollingsworth; Nicho ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 538 KB

DNA fingerprinting can be used to detect genetic rearrangements in cancer that may be associated with activation of oncogenes and inactivation of tumour suppressor genes. We have developed a fingerprinting strategy based on polymerase chain reaction (PCR) amplification of genomic DNA with primers sp