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Alternatively Spliced Protein Variants as Potential Therapeutic Targets for Male Infertility and Contraception

✍ Scribed by MARGARIDA FARDILHA; WENJUAN WU; ROSÁLIA SÁ; SARA FIDALGO; CRISTINA SOUSA; CATARINA MOTA; ODETE A.B. DA CRUZ E SILVA; EDGAR F. DA CRUZ E SILVA

Book ID: 111478970
Publisher: John Wiley and Sons
Year: 2004
Tongue: English
Weight: 251 KB
Volume: 1030
Category: Article
ISSN: 0890-6564
DOI: 10.1196/annals.1329.059

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## Abstract Deregulation of protein synthesis plays a critical role in cell transformation. Several translation initiation factors (eIFs) have been implicated in malignant transformation; thus, suppression of eIFs could be a potential cancer therapy if cancer cells are selectively killed without da