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Alternative splicings on p53, BRCA1 and PTEN genes involved in breast cancer

✍ Scribed by Naoko Okumura; Hitomi Yoshida; Yasuko Kitagishi; Yuri Nishimura; Satoru Matsuda

Book ID
116302289
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
411 KB
Volume
413
Category
Article
ISSN
0006-291X

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BRCA1 is a tumour suppressor gene located on chromosome band 17q21. It is estimated that mutations in the BRCA1 gene account for approximately 45% of the breast cancer families and almost all of the breast/ovarian cancer families. We have used single strand conformation polymorphism analysis, direct