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Alternative splicing takes shape during neuronal development

✍ Scribed by Paula Grabowski


Book ID
116505488
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
626 KB
Volume
21
Category
Article
ISSN
0959-437X

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## Abstract Cardiac troponin T (cTNT) exon 5 splicing is developmentally regulated such that it is included in embryonic but not adult heart. CUG‐BP and ETR‐3‐like factor (CELF) proteins promote exon inclusion, whereas polypyrimidine tract binding protein (PTB) and muscleblind‐like (MBNL) proteins