✦ LIBER ✦
Alternative Solid-Phase Strategies for the Efficient Labelling of Peptides with (Bathophenanthroline)ruthenium(II) Complexes
✍ Scribed by Rolf A. Kramer; Willi Bannwarth
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- German
- Weight
- 320 KB
- Volume
- 92
- Category
- Article
- ISSN
- 0018-019X
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✦ Synopsis
Abstract
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To increase the flexibility for the insertion of highly sensitive and robust [Ru^II^(bathophenanthroline)] complexes into peptides, we have evaluated three different solid‐phase strategies (bathophenanthroline=4,7‐diphenyl‐1,10‐phenanthroline). Among these, insertion of the Ru‐complex‐modified lysine building block 9 turned out to be the method of choice (Scheme 5).