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Alternative Models for Estrogen and Androgen Regulation of Human Breast Cancer Cell (T47D) Growth

✍ Scribed by CONSTANCE C. REESE; MEREDITH L. WARSHAW; JAMES T. MURAI; PENTTI K. SIITERI


Book ID
119862249
Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
485 KB
Volume
538
Category
Article
ISSN
0890-6564

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ALTERED PHENOTYPIC CHARACTERISTICS OF T4
✍ Pat Fernandez; Cody Wilson; Debie Hoivik; Stephen H. Safe πŸ“‚ Article πŸ“… 1998 πŸ› Elsevier Science 🌐 English βš– 314 KB

T47D human breast cancer cells were cultured in estrogen-deficient media for up to 32 months and the resulting cell line (L(hE(-))) exhibited unique phenotypic and genotypic characteristics. Compared to low passage (L) cells, the L(hE(-)) cells exhibited a significantly higher rate of proliferation,