✦ LIBER ✦
Alternative labelling of the cocaine analogue isomers α-CIT and β-CIT by direct iodination with no-carrier-added Na125I
✍ Scribed by Lars Müller; Christer Halldin; Carl-Gunnar Swahn; Christian Foged
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- French
- Weight
- 372 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
An alternative labelling of the cocaine analogue isomers α‐CIT and β‐CIT with no‐carrier‐added ^125^I by direct iodination of 2α‐ and 2β‐carbomethoxy‐3β‐phenyltropane with Na^125^I / sulfuric acid / nitric acid / acetic acid and peracetic acid under different reaction conditions, is described. The maximum radiolabelling yield obtained with the two isomers was 48% for [^125^I]α‐CIT and 28% for [^125^I]β‐CIT.