Mutations in DNA polymerase η are not de
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Eitan Glick; Lisa M. White; Nathan A. Elliott; Daniel Berg; Nancy B. Kiviat; Law
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Article
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2006
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John Wiley and Sons
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French
⚖ 102 KB
👁 1 views
## Abstract The major etiological agent in skin cancer is exposure to UV‐irradiation and the concomitant DNA damage. UV‐induced DNA lesions, such as thymine dimers, block DNA synthesis by the major DNA polymerases and inhibit the progression of DNA replication. Bypass of thymine dimers and related