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Alternative complement pathway assessment in patients with atypical HUS

✍ Scribed by Lubka T. Roumenina; Chantal Loirat; Marie-Agnes Dragon-Durey; Lise Halbwachs-Mecarelli; Catherine Sautes-Fridman; Veronique Fremeaux-Bacchi


Book ID
113717934
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
994 KB
Volume
365
Category
Article
ISSN
0022-1759

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Mutations in alternative pathway complem
✍ Tara K. Maga; Carla J. Nishimura; Amy E. Weaver; Kathy L. Frees; Richard J.H. Sm πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 199 KB

Atypical hemolytic uremic syndrome (aHUS) is characterized by acute renal failure, thrombocytopenia and microangiopathic hemolytic anemia, and occurs with an estimated incidence in the USA of 2 per 1,000,000. Disease pathogenesis is related to dysregulation of the alternative pathway (AP) of the com