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Alternation of extracellular matrix remodeling and apoptosis by activation of the aryl hydrocarbon receptor pathway in human periodontal ligament cells

✍ Scribed by Atsushi Tomokiyo; Hidefumi Maeda; Shinsuke Fujii; Satoshi Monnouchi; Naohisa Wada; Kiyomi Hori; Katsuaki Koori; Naohide Yamamoto; Yoko Teramatsu; Akifumi Akamine

Book ID: 115558559
Publisher: John Wiley and Sons
Year: 2012
Tongue: English
Weight: 731 KB
Volume: 113
Category: Article
ISSN: 0730-2312
DOI: 10.1002/jcb.24186

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## Abstract Unconjugated bilirubin (UCB), the end product of heme catabolism, causes apoptosis in cells of the central nervous system, endothelial cells, and hepatotoma cells. However, the molecular mechanisms that contribute to UCB cytotoxicity remain unclear. The purpose of this study was to char