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Alternate interferon signaling pathways

โœ Scribed by Dhananjaya V. Kalvakolanu

Book ID
114129374
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
686 KB
Volume
100
Category
Article
ISSN
0163-7258

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We have previously shown that cholestasis and bile acids inhibit 2ะˆ,5ะˆ oligoadenylate synthetase (OAS) activity in the liver and in primary hepatocyte cultures. Here, we assessed the influence of bile acids on interferon (IFN) pathway activation in three hepatoma cell lines. In HepG2 cells, bile aci