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Altering DNA-binding specificity of GAL4 requires sequences adjacent to the zinc finger

โœ Scribed by Corton, J. Christopher


Book ID
109760937
Publisher
Nature Publishing Group
Year
1989
Tongue
English
Weight
489 KB
Volume
340
Category
Article
ISSN
0028-0836

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## Abstract A peptide corresponding to the three zinc finger domains of the human transcription factor Sp1 has been expressed and found to bind a consensus Sp1 binding site with the sequence 5โ€ฒโ€GGGGCGGGGโ€3โ€ฒ. Examination of the amino acid distributions within a large zinc finger sequence data base a