Altered Th responses to a spontaneous low-pathogenic variant of Theiler's murine encephalomyelitis virus

Treatment with lipopolysaccharide enhanc

Treatment with lipopolysaccharide enhances the pathogenicity of a low-pathogenic variant of Theiler's murine encephalomyelitis virus

✍ J.P. Palma; S.H. Park; B.S. Kim 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 1016 KB

Intracerebral infection of susceptible mouse strains with Theiler's murine encephalomyelitis virus (TMEV) results in an immune-mediated demyelinating disease (TMEV-IDD) similar to human multiple sclerosis (MS). Although the etiology of MS remains unknown, a role of an infectious agent has been impli