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Altered synaptic plasticity in the nucleus accumbens of cocaine-withdrawn rats

✍ Scribed by Shigenobu Toda; Hao-wei Shen; Sakurako Kosugi; Khaled Moussawi; Ashley Bouknight; Aida Mammadova; Daniel S. Zahm; Peter W. Kalivas


Book ID
116776624
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
70 KB
Volume
65
Category
Article
ISSN
0168-0102

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This review focuses on cocaine-induced postsynaptic plasticity in the nucleus accumbens (NAc) involving changes in AMPA receptor (AMPAR) transmission. First, fundamental properties of AMPAR in the NAc are reviewed. Then, we provide a detailed and critical analysis of literature demonstrating alterat