Altered protein kinase C activity in different subfields of hippocampus following cerebral ischemia
✍ Scribed by Zoltán Oláh; Junichi Ikeda; Wayne B. Anderson; Ferenc Joó
- Publisher
- Springer
- Year
- 1990
- Tongue
- English
- Weight
- 656 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0364-3190
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Protein kinase C (PKC) is highly concentrated in the hippocampus and is thus a possible neural substrate of learning and memory. This study was designed to determine whether partial acquisition (i.e., the minimal amount of training leading to above-chance performance) of a spatial discrimination in
Protein kinase C (PKC) involvement in ischemia-induced neuronal damage has been investigated in superfused rat cerebral cortex slices submitted to 15 min of oxygen-glucose deprivation (OGD) and in primary cultures of rat cortical neurons exposed to 100 microM glutamate (GLU) for 10 min. OGD signific