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Altered Pharmacokinetics of Paclitaxel in Experimental Hepatic or Renal Failure

✍ Scribed by Mari Jiko; Ikuko Yano; Masahiro Okuda; Ken-ichi Inui

Publisher
Springer US
Year
2005
Tongue
English
Weight
166 KB
Volume
22
Category
Article
ISSN
0724-8741

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Comparative study on altered hepatic met
Comparative study on altered hepatic metabolism of CYP3A substrates in rats with glycerol-induced acute renal failure
✍ Jun-ichi Kusaba; Noriko Kajikawa; Hiromu Kawasaki; Yuji Kurosaki; Tetsuya Aiba πŸ“‚ Article πŸ“… 2012 πŸ› John Wiley and Sons 🌐 English βš– 147 KB πŸ‘ 2 views

To examine the mechanism accounting for the diverse alteration of hepatic metabolism of CYP3A substrates observed with renal function being severely impaired, the hepatic drug metabolizing activity was evaluated using liver microsomes prepared from rats with glycerol-induced acute renal failure (ARF