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Altered neurotransmitter receptor expression in transgenic mouse models of Huntington's disease

✍ Scribed by Cha, J.-H. J.; Frey, A. S.; Alsdorf, S. A.; Kerner, J. A.; Kosinski, C. M.; Mangiarini, L.; Penney, J. B.; Davies, S. W.; Bates, G. P.; Young, A. B.

Book ID
120152759
Publisher
The Royal Society
Year
1999
Tongue
English
Weight
344 KB
Volume
354
Category
Article
ISSN
0080-4622

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## Abstract Huntington disease (HD) is an autosomal dominant disorder in which degeneration of medium‐sized spiny striatal neurons occurs. The HD gene and the protein it encodes, huntingtin, have been identified but their functions remain unknown. Transgenic mouse models for HD have been developed