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Altered neuronal nitric oxide synthase expression in the cerebellum of calcium channel mutant mice

✍ Scribed by Im Joo Rhyu; Sang-Soep Nahm; Seung Jun Hwang; Hyun Kim; Young-Suk Suh; Sen-Ich Oda; Tamy C. Frank; Louise C. Abbott

Book ID
113999263
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
763 KB
Volume
977
Category
Article
ISSN
0006-8993

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A free radical, nitric oxide (NO), besides being a messenger molecule in the brain, becomes a neurotoxin if overproduced. We recently reported that methylmercury (MeHg) induces neuronal NO synthase (nNOS) in Purkinje cells. In the present study, we examined the distribution and the mechanism of nNOS