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Altered Muscarinic and Nicotinic Receptor Densities in Cortical and Subcortical Brain Regions in Parkinson's Disease

✍ Scribed by K. W. Lange; F. R. Wells; P. Jenner; C. D. Marsden

Book ID
111177953
Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
823 KB
Volume
60
Category
Article
ISSN
0022-3042

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## Abstract Neurodegeneration in clinically manifest Parkinson's disease affects the substantia nigra pars compacta, and gradually spreads to the limbic cortices and the neocortex. We used MRI imaging coupled with automated surface reconstruction and segmentation methods to examine cortical thickne