๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Altered lymphocyte reactivity in rheumatoid arthritis

โœ Scribed by H. Arthur Silverman; John S. Johnson; John H. Vaughan; James C. McGlamory

Publisher
John Wiley and Sons
Year
1976
Tongue
English
Weight
536 KB
Volume
19
Category
Article
ISSN
0004-3591

No coin nor oath required. For personal study only.

โœฆ Synopsis

Abstract

Blastogenic transformation of peripheral lymphocytes with phytohemagglutinin (PHA), conconavalin A (Con A), and pokeweed mitogen (PWM) was studied in 29 patients with rheumatoid arthritis (RA). The PHA response was depressed in a subgroup of RA patients with erosive disease. The Con A response was also depressed and paralleled the PHA response. The PWM response was not depressed. These results lend support to the hypothesis of a functional defect of cellular immunity in RA. It was shown that lymphocyte responsiveness to a single mitogen concentration is not an adequate assessment of the overall responsiveness of the lymphocytes tested.

๐Ÿ“œ SIMILAR VOLUMES

Lymphocyte populations in rheumatoid art
Lymphocyte populations in rheumatoid arthritis
โœ Arnold J. Rawson; T. C. Huang ๐Ÿ“‚ Article ๐Ÿ“… 1976 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 409 KB ๐Ÿ‘ 1 views
Lymphocyte Involvement in Rheumatoid Art
Lymphocyte Involvement in Rheumatoid Arthritis
โœ H. E. Paulus; H. I. Machleder; S. Levine; D. T. Y. Yu; N. S. Macdonald ๐Ÿ“‚ Article ๐Ÿ“… 1977 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 993 KB

## Abstract Grip strength, ring size, duration of morning stiffness, and the number of tender joints improved significantly in 9 patients with severe rheumatoid arthritis during prolonged continuous removal of thoracic duct lymphocytes through a surgical fistula. There was no improvement in 4 subje