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Altered levels of tissue gangliosides and glycoproteins in the infantile form of GM1-gangliosidosis

โœ Scribed by Bruno Berra; Sylvia Di Palma; Eric G. Brunngraber


Book ID
115820539
Publisher
Elsevier Science
Year
1974
Tongue
English
Weight
427 KB
Volume
57
Category
Article
ISSN
0009-8981

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GM1-gangliosidosis is a lysosomal storage disorder caused by a deficiency of beta-galactosidase. It is mainly characterized by progressive neurodegeneration and in its most severe infantile form it leads to death before the age of four. We have performed molecular analysis of five patients with the