Altered layer-specific gene expression in cortical samples from patients with temporal lobe epilepsy
โ Scribed by Laura Rossini; Ramona F. Moroni; Laura Tassi; Akiya Watakabe; Tetsuo Yamamori; Roberto Spreafico; Rita Garbelli
- Book ID
- 109113356
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 2011
- Tongue
- English
- Weight
- 933 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0013-9580
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## Abstract Temporal lobe epilepsy (TLE) is the most common form of partial epilepsy and affects 40% of the patients. Seizures arising from the mesial temporal lobe structures (i.e., amygdala and hippocampus) are common, whereas neocortical seizures are rare. In recent years, many studies aimed to
The expression of brain-derived neurotrophic factor and the โฃ subunit of calcium/ calmodulin-dependent protein kinase II mRNA in hippocampi obtained during surgical resections for intractable temporal lobe epilepsy were examined. Both calcium/calmodulindependent protein kinase II and brain-derived n