Altered K+movement in liver mitochondria from alloxan diabetic rats
β Scribed by R. A. Garrick
- Book ID
- 105405321
- Publisher
- Springer
- Year
- 1986
- Tongue
- English
- Weight
- 269 KB
- Volume
- 42
- Category
- Article
- ISSN
- 1420-682X
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## Abstract Liver mitochondria from normal and alloxan diabetic rats, isolated in 0.25 M sucrose, were assayed with an oxygen electrode for ADP/O and Ca^+2^/O ratios, respiratory ratio, and respiratory control index. Mitochondria were incubated with two substrates, succinate and Ξ²βhydroxybutyrate;
Covalent binding of reactive metabolites of 14CCl4 were found 1 or 3 h after treatment with the solvent in the lipid and protein fractions of highly purified liver mitochondrial of rats. Most of the label was found in the phospholipid (PL) fraction, much less in cholesterol esters (ChE), and only mi