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Altered innate and adaptive immune responses in patients with hidradenitis suppurativa

✍ Scribed by E.J. Giamarellos-Bourboulis; A. Antonopoulou; C. Petropoulou; M. Mouktaroudi; E. Spyridaki; F. Baziaka; A. Pelekanou; H. Giamarellou; N.G. Stavrianeas

Book ID
108669108
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
557 KB
Volume
156
Category
Article
ISSN
0007-0963

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Background: CBir1 is a dominant antigen with a role in innate and adaptive immunity in mouse models of colitis and antibodies to CBir1 are associated with severe human Crohn's disease (CD). Our aim was to determine whether CBir1 stimulates innate and antigen-specific T-cell responses in CD. We demon