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Altered I-J Phenotype in EαTransgenic Mice

✍ Scribed by Patrick M. Flood, Christophe Benoist, Diane Mathis and Donal B. Murphy

Book ID
123633578
Publisher
National Academy of Sciences
Year
1986
Tongue
English
Weight
325 KB
Volume
83
Category
Article
ISSN
0027-8424

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The A.CA strain (H-2f) lacks expression of the class II E molecule because of a stop codon in the leader sequence of the Ea gene and defective transcription of the Eb gene (Vu et al. 1989;Tacchini-Cottier et al. 1988). We previously reported that A.CA mice possessing an Ea d transgene express the Eo