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Altered frequency of initiation sites of DNA replication in Werner's syndrome cells

✍ Scribed by Fujio Takeuchi; Fumio Hanaoka; Makoto Goto; Ieo Akaoka; Tada-aki Hori; Masa-atsu Yamada; Terumasa Miyamoto


Book ID
104813184
Publisher
Springer
Year
1982
Tongue
English
Weight
427 KB
Volume
60
Category
Article
ISSN
0340-6717

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## Abstract We investigated the cloning efficiency, DNA repair, and the rate of DNA replication in the skin fibroblasts from patients with Werner's syndrome (WS) of an autosomal recessive premature aging disease. Five WS strains exhibited normal levels of sensitivity toward X‐ray and UV killings an