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Altered expression of TPP1 in fibroblast-like synovial cells might be involved in the pathogenesis of rheumatoid arthritis

✍ Scribed by Qing, Yu-Feng; Zhou, Jing-Guo; Zhao, Ming-Cai; Xie, Wen-Guang; Yang, Qi-Bin; Xing, Yan; Zeng, Sheng-Ping; Jiang, Hong

Book ID
113029015
Publisher
Springer
Year
2011
Tongue
English
Weight
461 KB
Volume
32
Category
Article
ISSN
0172-8172

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## Abstract ## Objective To investigate the roles of MAPKs and NF‐κB in tumor necrosis factor Ξ± (TNFΞ±)–induced expression of vascular cell adhesion molecule 1 (VCAM‐1) in human rheumatoid arthritis synovial fibroblasts (RASFs). ## Methods Human RASFs were isolated from synovial tissue obtained f