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Altered expression of preproenkephalin and prodynorphin mRNA in a genetic model of paroxysmal dystonia

✍ Scribed by J.N Nobrega; J.H Parkes; P Wong; R Raymond; A Richter

Book ID
113499736
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
270 KB
Volume
1015
Category
Article
ISSN
0006-8993

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The dt(sz) hamster is a well-established animal model of idiopathic paroxysmal dystonia. Previous investigations of this mutant have indicated dysfunctions of the gamma-aminobutyric acid (GABA)-ergic system within the basal ganglia. Systemic administration of the central stimulant pentylenetetrazole