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Altered expression of MicroRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis

✍ Scribed by Joanna Stanczyk; Deena M. Leslie Pedrioli; Fabia Brentano; Olga Sanchez-Pernaute; Christoph Kolling; Renate E. Gay; Michael Detmar; Steffen Gay; Diego Kyburz

Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
152 KB
Volume
58
Category
Article
ISSN
0004-3591

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## Abstract ## Objective To determine the role and expression of the cytokine/receptor pair interleukin‐21 (IL‐21)/IL‐21 receptor (IL‐21R) in rheumatoid arthritis (RA). ## Methods The expression of IL‐21R and IL‐21 was analyzed by TaqMan real‐time polymerase chain reaction (PCR) and in situ hybr