Altered expression of insulins I and II and their mRNAs in the islets of Langerhans in dexamethasone-induced diabetic rats

Uptake of circulating insulin-like growt

Uptake of circulating insulin-like growth factor-I into the cerebrospinal fluid of normal and diabetic rats and normalization of IGF-II mRNA content in diabetic rat brain

✍ C.S. Armstrong; L. Wuarin; D.N. Ishii 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 192 KB 👁 2 views

Brain injury has been prevented recently by systemic administration of human insulin-like growth factor-I (hIGF-I). It is widely believed that protein neurotrophic factors do not enter the brain from blood, and the mechanism by which circulating hIGF-I may be neuroprotective is uncertain. This inves