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Altered expression of epimorphin in intestinal myofibroblasts affects crypt-villus morphogenesis

โœ Scribed by Christine Fritsch; Elzbieta A. Swietlicki; Michele Kedinger; Marc S. Levin; Deborah C. Rubin


Book ID
119429294
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
195 KB
Volume
120
Category
Article
ISSN
0016-5085

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Background: Wnt signaling regulates intestinal epithelial stem cell function. Wnt ligands bind Frizzled (Fz) receptors and lowdensity lipoprotein-receptor-related protein (LRP) 5 and 6. Secreted Frizzled-related protein (SFRP) and Dickkopf families inhibit Wnt signaling. Our aim was to study express