Altered expression of complement receptors as a pathogenetic factor in systemic lupus erythematosus
β Scribed by James G. Wilson; Douglas T. Fearon
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 787 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0004-3591
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π SIMILAR VOLUMES
We have previously described associations between an allele of the interleukin-1 receptor antagonist gene (ILlRN) and several inflammatory diseases. In this study we tested the ILlRN gene as a possible marker in patients with systemic lupus erythematosus (SLE). Methods. Eighty-one SLE patients and
## Abstract ## Objective C4βderived activation fragments are the only complement ligands present on the surfaces of normal erythrocytes. The significance of this observation is unknown, and the role of erythrocyteβbound C4 (EβC4) in human disease has not been explored. More than any other human di