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Altered drug–serum protein binding in the genetically obese Zucker rat

✍ Scribed by I. H. Benedek; R. A. Blouin; P. J. McNamara


Publisher
John Wiley and Sons
Year
1985
Tongue
English
Weight
498 KB
Volume
74
Category
Article
ISSN
0022-3549

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The serum protein binding of phenytoin, salicylic acid, sulfisoxazole, and warfarin was determined in normal human adults, in patients with impaired renal function (kidney donor and recipient), and in adult male Sprague--Dawley rats. The free fraction values for salicylate and sulfisoxazole were sig