Altered distribution of caveolin-1 in early liver steatosis
โ Scribed by Maria Mastrodonato; Giuseppe Calamita; Roberta Rossi; Donatella Mentino; Leonilde Bonfrate; Piero Portincasa; Domenico Ferri; Giuseppa E. Liquori
- Book ID
- 108714126
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 686 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0014-2972
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We investigated the hepatocellular peroxisomes in 27 patients with steatosis of the liver by means of catalase cytochemistry, light and electron microscopic study, and morphometry. Seven normal human livers were used as controls. In our patients, fatty liver was mainly associated with alcohol abuse
## Background: Caveolin-1 is a key structural and functional protein for plasmalemmal invaginations termed caveolae. caveolin-1 is known to modulate multiple signal-transducing pathways involved in cell differentiation and proliferation. psoriasis is viewed as a multifactorial pathology characteriz