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Altered cyclophosphamide and thiotepa pharmacokinetics in a patient with moderate renal insufficiency

✍ Scribed by Corine Ekhart; J. Martijn Kerst; Sjoerd Rodenhuis; Jos H. Beijnen; Alwin D. R. Huitema


Book ID
105992911
Publisher
Springer
Year
2008
Tongue
English
Weight
250 KB
Volume
63
Category
Article
ISSN
0344-5704

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Cyclophosphamide pharmacokinetics and do
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## Background: Intravenous pulse administration of cyclophosphamide (cyc) has been successfully used for the treatment of various autoimmune diseases. these patients often present with impaired renal function or even end-stage renal failure. nevertheless, data concerning pharmacokinetics of cyc in