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Altered CNS response to injury in the MRL/MpJ mouse

✍ Scribed by D.W Hampton; A Seitz; P Chen; E Heber-Katz; J.W Fawcett


Book ID
116786494
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
691 KB
Volume
127
Category
Article
ISSN
0306-4522

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## Abstract Three genetic mouse models were examined to define effects of bone morphogenetic protein (BMP) signalling on gene expression in normal and injured adult brain. CaMKII‐Cre eliminated the BMP receptor Acvr1 (Alk2) and the common TGFΞ² superfamily signal mediator Smad4 or activated a consti