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Altered CD45 Expression in Malignant B-1 Cells

โœ Scribed by Anju M. Dang; Joy A. Phillips; T. Lin; Elizabeth S. Raveche

Book ID
112239514
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
214 KB
Volume
169
Category
Article
ISSN
0008-8749

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CD45 is a glycoprotein expressed in all lymphohemopoietic cells. Its expression increases during B-lymphocyte ontogeny. Few data are available about CD45 expression in the various types of low-grade B-cell non-Hodgkin's lymphomas (NHL). Low levels of CD45 have been reported in pathologic lymphocytes

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Altered expression of CD45 isoforms in differentiation of acute myeloid leukemia
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## Specific expression of different CD45 isoforms can be seen in various stages of differentiation of normal nucleated hematopoietic cells. Association of membrane expression of CD45 isoforms and differential levels of leukemia cells was studied in 91 cases with de novo acute myeloid leukemia (AML