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Altered Calcium-Mediated Cell Signaling in Keratinocytes Cultured from Patients with Neurofibromatosis Type 1

✍ Scribed by Timo Korkiamäki; Heli Ylä-Outinen; Jussi Koivunen; Seija-Liisa Karvonen; Juha Peltonen


Book ID
117021122
Publisher
American Society for Investigative Pathology
Year
2002
Tongue
English
Weight
972 KB
Volume
160
Category
Article
ISSN
0002-9440

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Neurofibromatosis type 1 (NF1) is characterized by clinical features that primarily affect tissues derived from the neural crest (neurofibromas, caf~-aulait macules). Because aberrant regulation of alternative splicing in the NF1 gene transcript may be of functional significance, cultured melanocyte