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Altered arginine metabolism in the central nervous system (CNS) of the Cln3−/− mouse model of juvenile Batten disease

✍ Scribed by C.-H. Chan; D. Ramirez-Montealegre; D. A. Pearce

Book ID
110852624
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
608 KB
Volume
35
Category
Article
ISSN
0305-1846

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Progressive oxidative damage in the cent
Progressive oxidative damage in the central nervous system of a murine model for juvenile Batten disease
✍ Jared W. Benedict; Crosby A. Sommers; David A. Pearce 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 531 KB

## Abstract Oxidative damage is a known contributor to the pathogenesis of neurodegenerative diseases. Juvenile Batten disease is a progressive neurodegenerative disorder of childhood that results from mutation in __Cln3__. We have performed an initial characterization of the oxidative burden throu