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Alterations of the FLT3 gene in acute promyelocytic leukemia: association with diagnostic characteristics and analysis of clinical outcome in patients treated with the Italian AIDA protocol

✍ Scribed by Noguera, N I; Breccia, M; Divona, M; Diverio, D; Costa, V; De Santis, S; Avvisati, G; Pinazzi, M B; Petti, M C; Mandelli, F


Book ID
110055280
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
279 KB
Volume
16
Category
Article
ISSN
0887-6924

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Internal tandem duplication and Asp835 m
✍ Lee-Yung Shih; Ming-Chung Kuo; Der-Cherng Liang; Chein-Fuang Huang; Tung-Liang L πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 122 KB πŸ‘ 2 views

## Abstract ## BACKGROUND The clinical relevance of mutations of the __FMS__‐like tyrosine kinase 3 (__FLT3__) gene in specific cytogenetic subgroups is not clear. The authors examined internal tandem duplication (ITD) and Asp835 mutations of __FLT3__ in patients with acute promyelocytic leukemia