𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Alterations of mitotic checkpoint genes play a role in embryonic chromosome mosaicism

✍ Scribed by R. Loper; N.R. Treff; J.C. Parks; R.T. Scott; W.B. Schoolcraft; M.G. Katz-Jaffe


Book ID
116477709
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
44 KB
Volume
94
Category
Article
ISSN
1556-5653

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Genetic alterations involving exon 3 of
✍ Bas P.L. Wijnhoven; Friedel Nollet; Nico J. De Both; Hugo W. Tilanus; Winand N.M πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 French βš– 268 KB πŸ‘ 1 views

␀-catenin has been identified as an oncogene. Phosphorylation of sites encoded by exon 3 of the ␀-catenin gene facilitates degradation of this protein by the adenomatous polyposis coli (apc) gene product. Mutations in these sites or inactivation of apc lead to stabilization of ␀-catenin, which then