Alterations of mitochondrial oxidative metabolism in rabbit urinary bladder after partial outlet obstruction
β Scribed by Ted Hueih-Shing Hsu; Robert M. Levin; Alan J. Wien; Niels Haugaard
- Publisher
- Springer
- Year
- 1994
- Tongue
- English
- Weight
- 546 KB
- Volume
- 141
- Category
- Article
- ISSN
- 0300-8177
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π SIMILAR VOLUMES
Bladder function is dependent upon cellular metabolism of substrates and the adequate generation of high-energy phosphate compounds. Partial outlet obstruction induces a marked decrease in bladder function which is associated with a significant decrease in the oxidative metabolism of glucose. The cu
Bladder outlet obstruction induces severe changes in urinary bladder function and metabolism. These changes are characterized by significant reductions in the ability of the in vitro whole bladder to generate pressure and to empty. Metabolically, partial outlet obstruction induces a shift from oxida
## Abstract ## Objectives Bladder outlet obstruction has shown to damage detrusor mitochondria with impaired detrusor contractility. One likely cause for mitochondrial injury is reactive oxygen species (ROS)βinduced damages, including lipid peroxidation injury. We designed this study to examine th