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Alterations of medial preoptic area neurons following pregnancy and pregnancy-like steroidal treatment in the rat

โœ Scribed by Lori Keyser-Marcus; Grace Stafisso-Sandoz; Kimberly Gerecke; Aaron Jasnow; Lawrence Nightingale; Kelly G Lambert; Jessica Gatewood; Craig H Kinsley

Book ID
117501658
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
310 KB
Volume
55
Category
Article
ISSN
0361-9230

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Neonatal treatment with tamoxifen causes immediate alterations of the sexually dimorphic nucleus of the preoptic area and medial preoptic area in male rats
โœ Vancutsem, Paul M.; Roessler, Michele L. ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 740 KB

Tamoxifen is an antiestrogen widely used for the treatment of breast cancer. Current evolutions in preventive strategies to include healthy premenopausal women warrant the study of its developmental toxicity. Perinatal treatment of male rodents with tamoxifen caused reproductive tract lesions and se