Alterations of Glutamate Transporter Gene Expression in Epileptic EL Mice Brains
β Scribed by Eiichi Katsumoto; Takahiro Ozaki; Toinoyuki Harada; Koji Mui; Sakae Yainagatni
- Book ID
- 109108353
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 2000
- Tongue
- English
- Weight
- 320 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0013-9580
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π SIMILAR VOLUMES
## Background: The neurotransmitter glutamate is involved in fast excitatory synaptic transmission in the mammalian brain. glutamate released from presynaptic terminals must be removed rapidly from the synaptic cleft by high affinity, sodium-dependent glutamate transporters to keep the extracellula
## Abstract Regulation of extracellular excitotoxins by glial and neuronal glutamate transporters is critical to maintain synaptic terminal integrity. Factors interfering with the normal functioning of these transporters might be involved in neurodegeneration. Among them, recent studies have shown