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Alterations of global histone H4K20 methylation during prostate carcinogenesis

✍ Scribed by Turang E Behbahani; Philip Kahl; Johannes von der Gathen; Lukas C Heukamp; Claudia Baumann; Ines Gütgemann; Bernhard Walter; Ferdinand Hofstädter; Patrick J Bastian; Alexander von Ruecker; Stefan C Müller; Sebastian Rogenhofer; Jörg Ellinger

Book ID
115017412
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
460 KB
Volume
12
Category
Article
ISSN
1471-2490

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## Abstract Epigenetic alterations play an important role in carcinogenesis. Recent studies suggested that global histone modifications are predictors of cancer recurrence in various tumor entities. Our study was performed to evaluate histone H3 lysine 4 mono‐methyl (H3K4me1), ‐di‐methyl (H3K4me2)