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Alterations of costimulatory molecules and instructive cytokines expressed by dendritic cells in the microenvironment of an endogenous mouse lymphoma

✍ Scribed by Naujoks, Marcella; Weiß, Jakob; Riedel, Tanja; Hömberg, Nadine; Przewoznik, Margarethe; Noessner, Elfriede; Röcken, Martin; Mocikat, Ralph

Book ID
125343463
Publisher
Springer-Verlag
Year
2014
Tongue
English
Weight
484 KB
Volume
63
Category
Article
ISSN
0340-7004

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## Abstract Steady‐state dendritic cells (DC) present peptide‐MHC complexes to T cells in a tolerogenic manner, presumably because of deficient costimulation. However, it is clear that the path to tolerance involves initial T cell activation, suggesting that the deficit may lie in late‐acting costi