G1 control gene status is frequently alt
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Daniel C. Betticher; Gavin R.M. White; Silvia Vonlanthen; Xuan Liu; Andreas Kapp
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Article
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1997
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John Wiley and Sons
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French
β 591 KB
Progression through the mammalian cell cycle is controlled by a series of cyclins, cyclin-dependent kinases (cdks) and cdk inhibitors. Cyclin D1, cdk4 and the tumour suppressors p16 and retinoblastoma protein (pRb) are thought to comprise a linked system governing cell passage through the G 1 phase