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Alterations of a dominant epitope of lymphocytic choriomeningitis virus which affect class I binding and cytotoxic T cell recognition

✍ Scribed by Catarina E. Hioe; Jeffrey A. Frelinger


Book ID
116097618
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
775 KB
Volume
32
Category
Article
ISSN
0161-5890

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Cytotoxic T lymphocytes (CTLs) cause specific destruction of allografts and viral-infected cells. While viral-restricted CTLs recognize viral peptides in association with class-I molecules encoded in the major histocompatibility complex, the role which peptides play during allorecognition remains ob