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Alterations in the main steps of reverse cholesterol transport in male patients with primary hypertriglyceridemia and low HDL-cholesterol levels

✍ Scribed by Fernando D Brites; Carla D Bonavita; Catherine De Geitere; Marcelo Cloës; Bernard Delfly; Mario J Yael; Jean-Charles Fruchart; Regina W Wikinski; Graciela R Castro


Book ID
119438749
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
180 KB
Volume
152
Category
Article
ISSN
0021-9150

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High prevalence of mutations in LCAT in
✍ Adriaan G. Holleboom; Jan A. Kuivenhoven; Frank Peelman; Alinda W. Schimmel; Jor 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 337 KB

Lecithin:cholesterol acyltransferase (LCAT) is crucial to the maturation of high-density lipoprotein (HDL). Homozygosity for LCAT mutations underlies rare disorders characterized by HDL-cholesterol (HDL-c) deficiency while heterozygotes have half normal HDL-c levels. We studied the prevalence of LCA