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Alterations in Salivary Antioxidants, Nitric Oxide, and Transforming Growth Factor-β1 in Relation to Disease Activity in Crohn's Disease Patients

✍ Scribed by ALI REZAIE; FAKHTEH GHORBANI; AZADEH ESHGHTORK; MOHAMMAD J. ZAMANI; GHOLAMREZA DEHGHAN; BARDIA TAGHAVI; SHEKOUFEH NIKFAR; AZADEH MOHAMMADIRAD; NASSER E. DARYANI; MOHAMMAD ABDOLLAHI


Book ID
111480710
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
121 KB
Volume
1091
Category
Article
ISSN
0890-6564

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Background: CD4 þ Foxp3 þ regulatory T cells (Treg) inhibit Tcell proliferation in vitro and are effective in suppressing colitis in mouse models. Tumor necrosis factor (TNF)-a, which is centrally involved in Crohn's disease (CD) pathogenesis, also impairs Treg function. Here we investigated the inf